References in the content below refer to the PBMEF Guide.
Definitions
Percent of children and adolescents (0–14 years) who were cured or completed treatment for DS-TB among the total number of children and adolescents (0–14 years) with new and relapse TB who were initiated on treatment for DS-TB during the same reporting period (excluding those moved to DR-TB treatment cohort).
Treatment outcomes are defined by the time of initiation on treatment; e.g., “2018 cohort successfully treated” reflect those who were initiated on treatment in 2018, even though treatment may have extended into 2019. For this reason, reports of treatment outcome data lag by one year. This indicator is a subset of the data reported in the core indicator “Treatment success rate.”
Calculation: (Numerator/Denominator) x 100
Numerator
Denominator
Ref # |
PEDS_TSR
|
Tier Level |
National Level Indicators
|
Category |
Cure
|
Type |
Outcome
|
Unit of Measure |
Percent of children
|
Data Type |
Percentage
|
Disaggregations |
Sex
|
Reporting Level |
National Level indicators should be reported at the national level; data may also be reported subnationally or at the project level if national data is not available.
|
Reporting Frequency |
This indicator should be reported on an annual basis at a minimum. More frequent monitoring on a quarterly or monthly basis is recommended.
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This indicator is reported by National TB Program (NTP) official records. Quarterly report on TB treatment outcomes in the basic management unit and Form 07: Combined annual outcomes report for basic TB and for RR-/multidrug-resistant (MDR)-TB.
TSR among children and adolescents aged 0–14 years is an important indicator of the quality of TB services, as it measures the NTP’s capacity to support young patients through a complete course of treatment with a favorable outcome. Successful treatment requires a stable supply of appropriate, child-friendly TB medications; management of side effects; and various efforts to support children with TB and their caregivers so they can complete the full course of treatment. This indicator measures the successful treatment of a cohort of people with TB, which is essential to reducing morbidity and mortality due to TB and to prevent the further spread of the infection. The TSR allows countries to monitor progress towards meeting global and national targets and to determine whether more resources are required to improve treatment outcomes by reducing death, loss to follow-up (LTFU), and the percent of people with an outcome that is not evaluated.
Detecting and successfully treating a large percent of people with TB should have an immediate impact on TB prevalence and mortality. Low TSRs may indicate inappropriate treatment regimens being administered, poor treatment management, adverse side effects, or comorbidities leading to death or LTFU. An understanding of why treatment success may be low is important to be able to implement solutions for improving patient care.
TB TSR in children and adolescents can be analyzed as a trend showing whether treatment success is stable, improving or decreasing over time, and to compare the rate to national and global TSR targets. A comparison of children with TB initiated on treatment and successfully completing treatment using a cascade of care will highlight the gap in the cascade where some people were lost during the treatment phase. The gap between treatment initiation and treatment success can be further broken down to understand why pediatric patients had unfavorable treatment outcomes (e.g., death, LTFU, treatment failure, or unknown outcomes).
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